BRAIN and NERVE－神経研究の進歩75巻11号

2023年11月発行

特集 アロスタシス—ホメオスタシスを超えて

神経内分泌からみたアロスタシスとレジリエンス

著者： 高柳友紀¹ 尾仲達史¹

所属機関： ¹自治医科大学医学部生理学講座神経脳生理学部門

ページ範囲：P.1205 - P.1209

文献概要

レジリエンスは困難な状況や逆境を乗り越える力（回復力）を示す言葉で，アロスタシスの視点で考察すると，アロスタシスを適切に関与させ，アロスタティック負荷／過負荷に至らせない，あるいはそこから恒常性を取り戻す能力のことである。この一連のストレス適応システムにオキシトシンが関わっている可能性が示されてきている。本論では内外環境の変化に応答するオキシトシンとその作用，レジリエンスの調節について論じる。

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