BRAIN and NERVE－神経研究の進歩76巻4号

2024年04月発行

特集 神経病理最前線

認知症疾患の神経病理

著者： 坂井健二¹ 山田正仁²

所属機関： ¹新潟県厚生農業協同組合連合会上越総合病院神経内科 ²国家公務員共済組合連合会九段坂病院内科（脳神経内科）

ページ範囲：P.333 - P.342

文献概要

認知症とは一度正常に発達した認知機能が後天的な脳の障害によって進行性・不可逆性に低下し，日常生活や社会生活に支障をきたすようになった状態である。中枢神経系を障害するさまざまな疾患（神経変性疾患，血管障害，感染症や炎症性疾患，脱髄性疾患，中毒・代謝性疾患，腫瘍や外傷など）により生じる。多くの神経疾患は神経病理学的に確定診断されるため，症例の病態の理解や高い精度の臨床診断には神経病理学的な理解が必須である。

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