ログイン
ランキング
お知らせ
ログイン
文献詳細
増大特集 末梢神経・筋肉の自己免疫性・炎症性疾患ハンドブック
第2章 疾患各論
文献概要
シェーグレン症候群はしばしば多彩な神経系合併症を伴い，その中でも末梢神経障害の頻度は高い。末梢神経障害の病型は，軸索障害型多発ニューロパチーや感覚失調性ニューロパチーなどさまざまであり，おのおのの病型の病態や鑑別診断について概説する。副腎皮質ステロイドや免疫グロブリン大量静注療法といった免疫治療は，病型ごとに治療反応性が異なる傾向にある。シェーグレン症候群に合併することのある筋炎についても紹介する。
参考文献
1）Jonsson R: Henrik Sjögren (1899-1986): the syndrome and his legacy. Ann Rheum Dis 80: 1108-1109, 2021
2）住田孝之: シェーグレン症候群. 医学のあゆみ258: 968-973, 2016
3）厚生労働省: 令和2年患者調査 疾病分類編（傷病別年次推移表）. 2020
4）藤林孝司, 菅井 進, 宮坂信之, 東條 毅, 宮脇昌二, 他: シェーグレン症候群改訂診断基準. 厚生省特定疾患免疫疾患調査研究班 平成10年度研究報告書. 1999, pp135-138
5）Shiboski CH, Shiboski SC, Seror R, Criswell LA, Labetoulle M, et al: 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome: a consensus and data-driven methodology involving three international patient cohorts. Ann Rheum Dis 76: 9-16, 2017
6）Tsuboi H, Hagiwara S, Asashima H, Takahashi H, Hirota T, et al: Comparison of performance of the 2016 ACR-EULAR classification criteria for primary Sjögren's syndrome with other sets of criteria in Japanese patients. Ann Rheum Dis 76: 1980-1985, 2017
7）Seror R, Bootsma H, Saraux A, Bowman SJ, Theander E, et al; EULAR Sjögren's Task Force: Defining disease activity states and clinically meaningful improvement in primary Sjögren's syndrome with EULAR primary Sjögren's syndrome disease activity (ESSDAI) and patient-reported indexes (ESSPRI). Ann Rheum Dis 75: 382-389, 2016
8）Liampas A, Parperis K, Erotocritou MF, Nteveros A, Papadopoulou M, et al: Primary Sjögren syndrome- related peripheral neuropathy: a systematic review and meta- analysis. Eur J Neurol 30: 255-265, 2023
9）Wu Z, Wang D, Chen L, Xianyu K, Yang H: Analysis of clinical features and risk factors of peripheral neuropathy in patients with primary Sjögren's syndrome. Eur J Med Res 28: 54, 2023［doi: 10.1186/s40001-023-01013-w］
10）Duda S, Witte T, Stangel M, Adams J, Schmidt RE, et al: Autoantibodies binding to stathmin-4: new marker for polyneuropathy in primary Sjögren's syndrome. Immunol Res 65: 1099-1102, 2017
11）Birnbaum J, Hoke A, Lalji A, Calabresi P, Bhargava P, et al: Brief Report: Anti-calponin 3 autoantibodies: a newly identified specificity in patients with Sjögren's syndrome. Arthritis Rheumatol 70: 1610-1616, 2018
12）小池春樹, 祖父江 元: シェーグレン症候群と末梢神経障害. Brain Nerve 65: 1333-1342, 2013
13）Gøransson LG, Herigstad A, Tjensvoll AB, Harboe E, Mellgren SI, et al: Peripheral neuropathy in primary Sjögren syndrome: a population-based study. Arch Neurol 63: 1612-1615, 2006
14）Kaltreider HB, Talal N: The neuropathy of Sjogren's syndrome. Trigeminal nerve involvement. Ann Intern Med 70: 751-762, 1969
15）Malinow K, Yannakakis GD, Glusman SM, Edlow DW, Griffin J, et al: Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjögren's syndrome. Ann Neurol 20: 535-537, 1986
16）Griffin JW, Cornblath DR, Alexander E, Campbell J, Low PA, et al: Ataxic sensory neuropathy and dorsal root ganglionitis associated with Sjögren's syndrome. Ann Neurol 27: 304-315, 1990
17）Mori K, Iijima M, Koike H, Hattori N, Tanaka F, et al: The wide spectrum of clinical manifestations in Sjögren's syndrome-associated neuropathy. Brain 128: 2518-2534, 2005
18）Sobue G, Yasuda T, Kumazawa K, Yamamoto K, Mitsuma T: MRI demonstrates dorsal column involvement of the spinal cord in Sjögren's syndrome-associated neuropathy. Neurology 45: 592-593, 1995
19）Birnbaum J, Lalji A, Saed A, Baer AN: Biopsy-proven small-fiber neuropathy in primary Sjögren's syndrome: neuropathic pain characteristics, autoantibody findings, and histopathologic features. Arthritis Care Res 71: 936-948, 2019
20）Ng Wing Tin S, Zouari HG, Wahab A, Sène D, Lefaucheur JP: Characterization of neuropathic pain in primary Sjögren's syndrome with respect to neurophysiological evidence of small-fiber neuropathy. Pain Med 20: 979-987, 2019
21）Ohyama K, Koike H, Takahashi M, Kawagashira Y, Iijima M, et al: Immunoglobulin G4-related pathologic features in inflammatory neuropathies. Neurology 85: 1400-1407, 2015
22）Kondo T, Inoue H, Usui T, Mimori T, Tomimoto H, et al: Autoimmune autonomic ganglionopathy with Sjögren's syndrome: significance of ganglionic acetylcholine receptor antibody and therapeutic approach. Auton Neurosci 146: 33-35, 2009
23）Colafrancesco S, Priori R, Gattamelata A, Picarelli G, Minniti A, et al: Myositis in primary Sjögren's syndrome: data from a multicentre cohort. Clin Exp Rheumatol 33: 457-464, 2015
24）Hirata K, Kobayashi M, Miyashita A, Yokota T: Steroid-responsive myositis in a patient with Sjögren's syndrome and refractory peripheral neuropathy. Neurol Sci 41: 1303-1305, 2020
25）Ramos-Casals M, Brito-Zerón P, Bombardieri S, Bootsma H, De Vita S, et al; EULAR-Sjögren Syndrome Task Force Group: EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies. Ann Rheum Dis 79: 3-18, 2020
26）Mekinian A, Ravaud P, Hatron PY, Larroche C, Leone J, et al: Efficacy of rituximab in primary Sjogren's syndrome with peripheral nervous system involvement: results from the AIR registry. Ann Rheum Dis 71: 84-87, 2012
27）Chen WH, Yeh JH, Chiu HC: Plasmapheresis in the treatment of ataxic sensory neuropathy associated with Sjögren's syndrome. Eur Neurol 45: 270-274, 2001
28）Caroyer JM, Manto MU, Steinfeld SD: Severe sensory neuronopathy responsive to infliximab in primary Sjögren's syndrome. Neurology 59: 1113-1114, 2002
29）Pindi Sala T, Villedieu M, Damian L, Crave JC, Pautot V, et al: Long- term efficacy of immunoglobulins in small fiber neuropathy related to Sjögren's syndrome. J Neurol 267: 3499- 3507, 2020
30）Kataria R, Suja L, Anil AA, Senthil N: Primary Sjogren's syndrome presenting as an isolated severe autonomic dysfunction treated with steroids. BMJ Case Rep 16: e256412, 2023［doi: 10.1136/bcr-2023-256412］
31）Sokmen O, Temucin CM, Ayhan Seker C, Tan E: Immunotherapy provides electrophysiological recovery and excellent clinical response in Sjögren's syndrome-linked quite severe autonomic neuropathy. Neurologist 28: 204-206, 2023
掲載誌情報
