BRAIN and NERVE－神経研究の進歩76巻5号

2024年05月発行

増大特集 末梢神経・筋肉の自己免疫性・炎症性疾患ハンドブック

第2章　疾患各論

末梢神経・筋サルコイドーシス

著者： 藤澤美和子¹

所属機関： ¹

ページ範囲：P.598 - P.604

文献概要

末梢神経，筋サルコイドーシスは非乾酪性類上皮細胞肉芽腫が脳神経と脊髄神経，骨格筋に出現する疾患である。画像検査を含め，全身検索と他疾患の除外が重要で，確定診断には非乾酪性類上皮細胞肉芽腫の証明が必須である。いずれも治療はステロイド薬が第一選択ではあるが，複数の免疫抑制薬，TNF-α阻害薬を併用しながら長期の治療を要することが多い。治療薬のランダム化比較試験に乏しく，治療法の確立が望まれる。

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