呼吸器ジャーナル72巻2号

2024年05月発行

特集 気管支拡張症—温故知新　注目され始めた一大カテゴリー Ⅰ．気管支拡張症の疫学と診断

気管支拡張症の疫学と診断の進め方

著者： 森本耕三¹ 伊藤優志¹

所属機関： ¹複十字病院呼吸器内科

ページ範囲：P.174 - P.182

POINT
●気管支拡張症は様々な原因によって生じる慢性呼吸器疾患である．
●有病率，原因疾患には地域差があるが，特発性，感染後が多い．
●正確な原因疾患同定のためにアルゴリズムを参考とする．
●本邦の気管支拡張症の増加には，女性の肺NTM症の増加が関与している．
●肺NTM症患者においても，気管支拡張症を来す原因疾患の鑑別を行う．

参考文献

1）Cole PJ. Inflammation : a two-edged sword--the model of bronchiectasis. Eur J Respir Dis Suppl 1986 ; 147 : 6-15.

2）Aliberti S, Goeminne PC, O'Donnell AE, et al. Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials : international consensus recommendations. Lancet Respir Med 2022 ; 10 : 298-306.

3）Zhou YM, Wang C, Yao WZ, et al. ［The prevalence and risk factors of bronchiectasis in residents aged 40 years old and above in seven cities in China］. Zhonghua Nei Ke Za Zhi 2013 ; 52 : 379-82.

4）Quint JK, Millett ER, Joshi M, et al. Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013 : a population-based cohort study. Eur Respir J 2016 ; 47 : 186-93.

5）Weycker D, Hansen GL, Seifer FD. Prevalence and incidence of noncystic fibrosis bronchiectasis among US adults in 2013. Chron Respir Dis 2017 ; 14 : 377-84.

6）Gao YH, Guan WJ, Liu SX, et al. Aetiology of bronchiectasis in adults : A systematic literature review. Respirology 2016 ; 21 : 1376-83.

7）Chalmers JD, Polverino E, Crichton ML, et al. Bronchiectasis in Europe : data on disease characteristics from the European Bronchiectasis registry（EMBARC）. Lancet Respir Med 2023 ; 11 : 637-49.

8）Kadowaki T, Yano S, Wakabayashi K, et al. An analysis of etiology, causal pathogens, imaging patterns, and treatment of Japanese patients with bronchiectasis. Respir Investig 2015 ; 53 : 37-44.

9）Asakura T, Morimoto K, Ito A, et al. Etiology and Health-Related Quality of Life in Non-Cystic Fibrosis Bronchiectasis and Nontuberculous Mycobacterial Pulmonary Disease : The First Analysis of the Japanese Nontuberculous Mycobacteriosis-Bronchiectasis Registry. B106 BREAKTHROUGHS IN NTM DIAGNOSIS AND TREATMENT. American Thoracic Society 2020 ; A4370-A70.

10）Morimoto K, Iwai K, Yoshiyama T, et al. Epidemiological characteristics of nontuberculous mycobacteriosis and bronchiectasis : comparative study using national mortality statistics from 1970 to 2015 in Japan. ERJ Open Res 2023 ; 9 : 00424-2022.

11）Fujita K, Ito Y, Hirai T, et al. Prevalence and risk factors for chronic co-infection in pulmonary Mycobacterium avium complex disease. BMJ Open Respir Res 2014 ; 1 : e000050.

12）Urabe N, Sakamoto S, Shimanuki Y, et al. Impact of chronic co-infection in pulmonary Mycobacterium avium complex disease after treatment initiation. BMC Pulm Med 2022 ; 22 : 157.

13）Dhar R, Singh S, Talwar D, et al. Bronchiectasis in India : results from the European Multicentre Bronchiectasis Audit and Research Collaboration（EMBARC）and Respiratory Research Network of India Registry. Lancet Glob Health 2019 ; 7 : e1269-79.

14）大石修司，人見秀昭，酒井正雄，他．Swyer-James症候群5例の臨床的検討．日胸疾患会誌1995 ; 33 : 1401-7.

15）Park MA, Li JT, Hagan JB, et al. Common variable immunodeficiency : a new look at an old disease. Lancet 2008 ; 372 : 489-502.

16）Hill AT, Sullivan AL, Chalmers JD, et al. British Thoracic Society guideline for bronchiectasis in adults. BMJ Open Respir Res 2018 ; 5 : e000348.

17）Du Q, Jin J, Liu X, et al. Bronchiectasis as a Comorbidity of Chronic Obstructive Pulmonary Disease : A Systematic Review and Meta-Analysis. PLoS One 2016 ; 11 : e0150532.

18）Metersky ML, Dransfield MT. The Chronic Obstructive Pulmonary Disease（COPD）-Bronchiectasis Overlap Syndrome : Does My COPD Patient Have Bronchiectasis on Computed Tomography? “Frankly, My Dear, I Don't Give a Damn!”. Am J Respir Crit Care Med 2023 ; 208 : 1265-7.

19）De Soyza A, McDonnell MJ, Goeminne PC, et al. Bronchiectasis Rheumatoid Overlap Syndrome Is an Independent Risk Factor for Mortality in Patients With Bronchiectasis : A Multicenter Cohort Study. Chest 2017 ; 151 : 1247-54.

20）Lin HC, Huang HY, Lin CY, et al. Clinical outcomes and prognostic factors of bronchiectasis rheumatoid overlap syndrome : A multi-institution cohort study. Front Med（Lausanne）2022 ; 9 : 1004550.

21）Pulmonology Portuguese Society Bronchiectasis Study Group. Recommendations for aetiological diagnosis of bronchiectasis. Rev Port Pneumol（2006）2016 ; 22 : 222-35.

22）Maldonado F, Tazelaar HD, Wang CW, et al. Yellow nail syndrome : analysis of 41 consecutive patients. Chest 2008 ; 134 : 375-81.

23）Krustins E. Mounier-Kuhn syndrome : a systematic analysis of 128 cases published within last 25 years. Clin Respir J 2016 ; 10 : 3-10.

24）Dunne MG, Reiner B. CT features of tracheobronchomegaly. J Comput Assist Tomogr 1988 ; 12 : 388-91.

25）Woodring JH, Howard RS 2nd, Rehm SR. Congenital tracheobronchomegaly（Mounier-Kuhn syndrome） : a report of 10 cases and review of the literature. J Thorac Imaging 1991 ; 6 : 1-10.

26）Black H, Mendoza M, Murin S. Thoracic manifestations of inflammatory bowel disease. Chest 2007 ; 131 : 524-32.

27）Kuzela L, Vavrecka A, Prikazska M, et al. Pulmonary complications in patients with inflammatory bowel disease. Hepatogastroenterology 1999 ; 46 : 1714-9.

28）Mikami Y, Grubb BR, Rogers TD, et al. Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration. Sci Transl Med 2023 ; 15 : eabo7728.

29）Araújo D, Shteinberg M, Aliberti S, et al. Standardised classification of the aetiology of bronchiectasis using an objective algorithm. Eur Respir J 2017 ; 50 : 1701289.

30）Cooke JC, Currie DC, Morgan AD, et al. Role of computed tomography in diagnosis of bronchiectasis. Thorax 1987 ; 42 : 272-7.

31）Finch S, McDonnell MJ, Abo-Leyah H, et al. A Comprehensive Analysis of the Impact of Pseudomonas aeruginosa Colonization on Prognosis in Adult Bronchiectasis. Ann Am Thorac Soc 2015 ; 12 : 1602-11.

32）Aksamit TR, O'Donnell AE, Barker A, et al. Adult Patients With Bronchiectasis : A First Look at the US Bronchiectasis Research Registry. Chest 2017 ; 151 : 982-92.

33）Pifferi M, Bush A, Caramella D, et al. Agenesis of paranasal sinuses and nasal nitric oxide in primary ciliary dyskinesia. Eur Respir J 2011 ; 37 : 566-71.

34）Polverino E, Goeminne PC, McDonnell MJ, et al. European Respiratory Society guidelines for the management of adult bronchiectasis. Eur Respir J 2017 ; 50 : 1700629.