icon fsr

文献詳細

雑誌文献

循環器ジャーナル65巻4号

2017年10月発行

文献概要

特集 ACSの診断と治療はどこまで進歩したのか Ⅰ.ACSの基礎知識

ACSの病理,ACS発症のメカニズム

著者: 大塚文之1

所属機関: 1国立循環器病研究センター心臓血管内科 冠疾患科

ページ範囲:P.574 - P.581

文献購入ページに移動
Point
・冠動脈血栓症の主たる成因はプラーク破裂で,ほかにプラークびらんやcalcified noduleも原因として知られる.
・ステント血栓症によるACS発症のメカニズムは,ステントの種類や留置期間によって様々である.

参考文献

1) Virmani R, Kolodgie FD, Burke AP, et al:Lessons from sudden coronary death:a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 20:1262-1275, 2000
2) Bentzon JF, Otsuka F, Virmani R, et al:Mechanisms of plaque formation and rupture. Circ Res 114:1852-1866, 2014
3) Yahagi K, Kolodgie FD, Otsuka F, et al:Pathophysiology of native coronary, vein graft, and in-stent atherosclerosis. Nat Rev Cardiol 13:79-98, 2016
4) Davies MJ, Thomas AC:Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina. Br Heart J 53:363-373, 1985
5) Kolodgie FD, Gold HK, Burke AP, et al:Intraplaque hemorrhage and progression of coronary atheroma. N Engl J Med 349:2316-2325, 2003
6) Otsuka F, Joner M, Prati F, et al:Clinical classification of plaque morphology in coronary disease. Nat Rev Cardiol 11:379-389, 2014
7) Kolodgie FD, Burke AP, Farb A, et al:The thin-cap fibroatheroma:a type of vulnerable plaque:the major precursor lesion to acute coronary syndromes. Curr Opin Cardiol 16:285-292, 2001
8) Libby P:Mechanisms of acute coronary syndromes and their implications for therapy. N Engl J Med 368:2004-2013, 2013
9) Burke AP, Farb A, Malcom GT, et al:Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. N Engl J Med 336:1276-1282, 1997
10) Siegel RJ, Swan K, Edwalds G, et al:Limitations of postmortem assessment of human coronary artery size and luminal narrowing:differential effects of tissue fixation and processing on vessels with different degrees of atherosclerosis. J Am Coll Cardiol 5:342-346, 1985
11) Farb A, Burke AP, Tang AL, et al:Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death. Circulation 93:1354-1363, 1996
12) Kramer MC, Rittersma SZ, de Winter RJ, et al:Relationship of thrombus healing to underlying plaque morphology in sudden coronary death. J Am Coll Cardiol 55:122-132, 2010
13) Schwartz RS, Burke A, Farb A, et al:Microemboli and microvascular obstruction in acute coronary thrombosis and sudden coronary death:relation to epicardial plaque histopathology. J Am Coll Cardiol 54:2167-2173, 2009
14) Otsuka F, Sakakura K, Yahagi K, et al:Has our understanding of calcification in human coronary atherosclerosis progressed? Arterioscler Thromb Vasc Biol 34:724-736, 2014
15) Nakano M, Yahagi K, Otsuka F, et al:Causes of Early Stent Thrombosis in Patients Presenting With Acute Coronary Syndrome:An Ex Vivo Human Autopsy Study. J Am Coll Cardiol 63:2510-2520, 2014
16) Kolandaivelu K, Swaminathan R, Gibson WJ, et al:Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings. Circulation 123:1400-1409, 2011
17) Otsuka F, Cheng Q, Yahagi K, et al:Acute Thrombogenicity of a Durable Polymer Everolimus-Eluting Stent Relative to Contemporary Drug-Eluting Stents With Biodegradable Polymer Coatings Assessed Ex Vivo in a Swine Shunt Model. JACC Cardiovasc Interv 8:1248-1260, 2015
18) Joner M, Finn AV, Farb A, et al:Pathology of drug-eluting stents in humans:delayed healing and late thrombotic risk. J Am Coll Cardiol 48:193-202, 2006
19) Nakazawa G, Finn AV, Vorpahl M, et al:Coronary responses and differential mechanisms of late stent thrombosis attributed to first-generation sirolimus-and paclitaxel-eluting stents. J Am Coll Cardiol 57:390-398, 2011
20) Otsuka F, Vorpahl M, Nakano M, et al:Pathology of second-generation everolimus-eluting stents versus first-generation sirolimus- and Paclitaxel-eluting stents in humans. Circulation 129:211-223, 2014
21) Virmani R, Guagliumi G, Farb A, et al:Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent:should we be cautious? Circulation 109:701-705, 2004
22) Nakazawa G, Finn AV, Vorpahl M, et al:Incidence and predictors of drug-eluting stent fracture in human coronary artery a pathologic analysis. J Am Coll Cardiol 54:1924-1931, 2009
23) Finn AV, Otsuka F:Neoatherosclerosis:a culprit in very late stent thrombosis. Circ Cardiovasc Interv 5:6-9, 2012
24) Nakazawa G, Otsuka F, Nakano M, et al:The pathology of neoatherosclerosis in human coronary implants:bare-metal and drug-eluting stents. J Am Coll Cardiol 57:1314-1322, 2011
25) Otsuka F, Byrne RA, Yahagi K, et al:Neoatherosclerosis:overview of histopathologic findings and implications for intravascular imaging assessment. Eur Heart J 36:2147-2159, 2015

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:2432-3292

印刷版ISSN:2432-3284

雑誌購入ページに移動
icon up
あなたは医療従事者ですか?