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雑誌文献

循環器ジャーナル66巻1号

2018年01月発行

文献概要

特集 循環器診療 薬のギモン—エキスパートに学ぶ薬物治療のテクニック Ⅱ.高血圧診療でのギモン

コントロール不良の早朝高血圧.薬剤選択,内服時間,どうしたらいいの?

著者: 本行一博1 山本浩一1 楽木宏実1

所属機関: 1大阪大学大学院医学系研究科老年・総合内科学

ページ範囲:P.58 - P.61

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・早朝高血圧は脳・臓器合併症や心血管リスクと有意に関連することが示されている.
・一方でその認識は十分とは言えず,また治療に難渋するケースも少なくない.
・本稿では,早朝高血圧の病態や意義,治療につき考察する.

参考文献

1) Fagard RH, Van Den Broeke C, De Cort P:Prognostic significance of blood pressure measured in the office, at home and during ambulatory monitoring in older patients in general practice. J Hum Hypertens 19:801-807, 2005
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3) Kario K, Ishikawa J, Pickering TG, et al:Morning hypertension:the strongest independent risk factor for stroke in elderly hypertensive patients. Hypertens Res 29:581-587, 2006
4) Kario K:Time for focus on morning hypertension:pitfall of current antihypertensive medication. Am J Hypertens 18:149-151, 2005
5) Kario K, Pickering TG, Umeda Y, et al:Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensives:a prospective study. Circulation 107:1401-1406, 2003
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7) Kario K:Morning surge in blood pressure and cardiovascular risk:evidence and perspectives. Hypertension 56:765-773, 2010
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10) Hoshide S, Kario K, de la Sierra A, et al:Ethnic differences in the degree of morning blood pressure surge and in its determinants between Japanese and European hypertensive subjects:data from the ARTEMIS study. Hypertens 66:750-756, 2015
11) Asayama K, Ohkubo T, Kikuya M, et al:Prediction of stroke by home “morning” versus “evening” blood pressure values:the Ohasama study. Hypertens 48:737-743, 2006
12) Nishinaga M, Takata J, Okumiya K, et al:High morning home blood pressure is associated with a loss of functional independence in the community-dwelling elderly aged 75 years or older. Hypertens Res 28:657-663, 2005
13) Li Y, Vgontzas AN, Fernandez-Mendoza J, et al:Insomnia with physiological hyperarousal is associated with hypertension. Hypertens 65:644-650, 2015
14) Kario K, Matsui Y, Shibasaki S, et al:An alpha-adrenergic blocker titrated by self-measured blood pressure recordings lowered blood pressure and microalbuminuria in patients with morning hypertension:the Japan Morning Surge-1 Study. J Hypertens 26:1257-1265, 2008
15) Ibuki C, Seino Y, Otsuka T, Mizuno K:The fixed-dose combination of losartan/hydrochlorothiazide elicits potent blood pressure lowering during nighttime in obese hypertensive patients. J Clin Med Res 6:8-16, 2014

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:2432-3292

印刷版ISSN:2432-3284

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