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循環器ジャーナル66巻1号

2018年01月発行

文献概要

特集 循環器診療 薬のギモン—エキスパートに学ぶ薬物治療のテクニック Ⅲ.虚血性心疾患・SHD診療でのギモン

PCI後の非心臓手術時にヘパリンによる“bridging therapy”は必要か?

著者: 粟田政樹1

所属機関: 1国立病院機構大阪医療センター循環器内科

ページ範囲:P.80 - P.84

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・冠動脈ステント留置後の非心臓手術時抗血小板療法については,出血性合併症およびステント血栓症発症時の臨床転帰の両者を評価し対応する.
・ヘパリン置換はステント血栓症の予防に有効・無効いずれのエビデンスはなく,周術期の出血性合併症を増加させるリスクがある.

参考文献

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9) Holmes DR Jr., Kereiakes DJ, Garg S, et al:Stent thrombosis. J Am Coll Cardiol 56:1357-1365, 2010
10) Chechi T, Vecchio S, Vittori G, et al:ST-segment elevation myocardial infarction due to early and late stent thrombosis a new group of high-risk patients. J Am Coll Cardiol 51:2396-2402, 2008
11) Siegal D, Yudin J, Kaatz S, et al:Periprocedural heparin bridging in patients receiving vitamin K antagonists:systematic review and meta-analysis of bleeding and thromboembolic rates. Circulation 126:1630-1639, 2012
12) Douketis JD, Spyropoulos AC, Kaatz S, et al:Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation. N Engl J Med 373:823-833, 2015
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掲載誌情報

出版社:株式会社医学書院

電子版ISSN:2432-3292

印刷版ISSN:2432-3284

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