循環器ジャーナル66巻3号

2018年07月発行

特集 肺高血圧症Cutting Edge Ⅱ．肺高血圧症：何が原因か，なぜ原因となるのか？

肺疾患で肺高血圧症が生じるメカニズム

著者： 辻野一三¹ 桑原健² 谷野美智枝²

所属機関： ¹北海道大学病院内科Ⅰ ²北海道大学医学部腫瘍病理学教室

ページ範囲：P.348 - P.352

Point
・肺疾患に伴う肺高血圧症は他群の肺高血圧症と比較し治療反応性や予後が不良である．
・本群の肺高血圧症の重要な特徴に，「低酸素性肺血管攣縮」「肺毛細血管床の減少」「肺静脈・毛細血管病変」がある．
・本疾患患者のQOLと予後改善のためには正しい病態の理解とそれに適合した治療戦略の構築と実践が求められる．

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