循環器ジャーナル66巻3号

2018年07月発行

特集 肺高血圧症Cutting Edge Ⅲ．肺高血圧症診断：診断のきっかけ，どんなサインが重要か？

呼吸機能検査と肺換気・血流シンチグラフィ

著者： 西村倫太郎¹ 田邉信宏¹²

所属機関： ¹千葉大学大学院医学研究院呼吸器内科学 ²千葉大学大学院医学研究院先端肺高血圧症医療学

ページ範囲：P.382 - P.390

Point
・肺高血圧症の診断において，呼吸機能検査は肺疾患による肺高血圧症の鑑別に必要である．
・慢性呼吸器疾患患者の呼吸機能検査において，換気障害に比べ重度の肺拡散能（DL_CO）低下を認める場合は肺高血圧症の合併を疑う．
・肺動脈性肺高血圧症（PAH）や慢性血栓塞栓性肺高血圧症（CTEPH）でも軽度の換気障害を認め，DL_COは予後規定因子である．
・肺高血圧症における肺換気・血流シンチグラフィは主にCTEPHの診断に用い，PAHや肺疾患に伴う肺高血圧症などの鑑別にも有用である．

参考文献

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