循環器ジャーナル67巻3号

2019年07月発行

特集 循環器疾患の画像診断—現状と進歩 Ⅱ．虚血性心疾患

冠動脈MRAと心筋パーフュージョンMRIの活用法

著者： 後藤義崇¹ 石田正樹¹ 佐久間肇¹

所属機関： ¹三重大学医学部附属病院放射線科

ページ範囲：P.356 - P.363

Point
・心臓MRI検査は，様々な情報を一度の検査で得ることができる画像診断法である．
・冠動脈MRAは放射線被曝がなく石灰化病変であっても狭窄が評価可能など冠動脈CTにはない特徴を有する．
・心筋パーフュージョンMRIはSPECTと比較し空間解像度が高く，虚血診断能および予後評価に優れている．

参考文献

1) 山岸正和，玉木長吉：慢性冠動脈疾患診断ガイドライン．2019

2) Kato S, Kitagawa K, Ishida N, et al:Assessment of coronary artery disease using magnetic resonance coronary angiography:a national multicenter trial. J Am Coll Cardiol 56:983-991, 2010

3) Budoff MJ, Dowe D, Jollis JG, et al:Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease:results from the prospective multicenter ACCURACY（Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography）trial. J Am Coll Cardiol 52:1724-1732, 2008

4) Nehrke K, Bornert P, Mazurkewitz P, et al:Free-breathing whole-heart coronary MR angiography on a clinical scanner in four minutes. J Magn Reson Imaging 23:752-756, 2006

5) Yoon YE, Kitagawa K, Kato S, et al:Prognostic value of coronary magnetic resonance angiography for prediction of cardiac events in patients with suspected coronary artery disease. J Am Coll Cardiol 60:2316-2322, 2012

6) Moghari MH, Roujol S, Henningsson M, et al:Three-dimensional heart locator for whole-heart coronary magnetic resonance angiography. Magn Reson Med 71:2118-2126, 2014

7) Aitken AP, Henningsson M, Botnar RM, et al:100% Efficient three-dimensional coronary MR angiography with two-dimensional beat-to-beat translational and bin-to-bin affine motion correction. Magn Reson Med 74:756-764, 2015

8) Pang J, Bhat H, Sharif B, et al:Whole-heart coronary MRA with 100% respiratory gating efficiency:self-navigated three-dimensional retrospective image-based motion correction（TRIM）. Magn Reson Med 71:67-74, 2014

9) He Y, Pang J, Dai Q, et al:Diagnostic Performance of Self-navigated Whole-Heart Contrast-enhanced Coronary 3-T MR Angiography. Radiology 281:401-408, 2016

10) Akçakaya M, Basha TA, Chan RH, et al:Accelerated isotropic sub-millimeter whole-heart coronary MRI:compressed sensing versus parallel imaging. Magn Reson Med 71:815-822, 2014

11) Kim WY, Astrup AS, Stuber M, et al:Subclinical coronary and aortic atherosclerosis detected by magnetic resonance imaging in type 1 diabetes with and without diabetic nephropathy. Circulation 115:228-235, 2007

12) Makowski MR, Henningsson M, Spuentrup E, et al:Characterization of coronary atherosclerosis by magnetic resonance imaging. Circulation 128:1244-1255, 2013

13) Kawasaki T, Koga S, Koga N, et al:Characterization of hyperintense plaque with noncontrast T（1）-weighted cardiac magnetic resonance coronary plaque imaging:comparison with multislice computed tomography and intravascular ultrasound. JACC Cardiovasc Imaging 2:720-728, 2009

14) Noguchi T, Kawasaki T, Tanaka A, et al:High-intensity signals in coronary plaques on noncontrast T1-weighted magnetic resonance imaging as a novel determinant of coronary events. J Am Coll Cardiol 63:989-999, 2014

15) Noguchi T, Tanaka A, Kawasaki T, et al:Effect of Intensive Statin Therapy on Coronary High-Intensity Plaques Detected by Noncontrast T1-Weighted Imaging:The AQUAMARINE Pilot Study. J Am Coll Cardiol 66:245-256, 2015

16) Asaumi Y, Noguchi T, Morita Y, et al:High-Intensity Plaques on Noncontrast T1-Weighted Imaging as a Predictor of Periprocedural Myocardial Injury. JACC Cardiovasc imaging 8:741-743, 2015

17) Greenwood JP, Maredia N, Younger JF, et al:Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease（CE-MARC）:a prospective trial. Lancet 379:453-460, 2012

18) Jaarsma C, Leiner T, Bekkers SC, et al:Diagnostic performance of noninvasive myocardial perfusion imaging using single-photon emission computed tomography, cardiac magnetic resonance, and positron emission tomography imaging for the detection of obstructive coronary artery disease:a meta-analysis. J Am Coll Cardiol 59:1719-1728, 2012

19) Lockie T, Ishida M, Perera D, et al:High-resolution magnetic resonance myocardial perfusion imaging at 3.0-Tesla to detect hemodynamically significant coronary stenoses as determined by fractional flow reserve. J Am Coll Cardiol 57:70-75, 2011

20) Takx RA, Blomberg BA, El Aidi H, et al:Diagnostic accuracy of stress myocardial perfusion imaging compared to invasive coronary angiography with fractional flow reserve meta-analysis. Circ Cardiovasc imaging 8:pii:e002666, 2015

21) Lipinski MJ, McVey CM, Berger JS, et al:Prognostic value of stress cardiac magnetic resonance imaging in patients with known or suspected coronary artery disease:a systematic review and meta-analysis. J Am Coll Cardiol 62:826-838, 2013

22) Gargiulo P, Dellegrottaglie S, Bruzzese D, et al:The prognostic value of normal stress cardiac magnetic resonance in patients with known or suspected coronary artery disease:a meta-analysis. Circ Cardiovasc Imaging 6:574-582, 2013

23) Steel K, Broderick R, Gandla V, et al:Complementary prognostic values of stress myocardial perfusion and late gadolinium enhancement imaging by cardiac magnetic resonance in patients with known or suspected coronary artery disease. Circulation 120:1390-1400, 2009

24) Greenwood JP, Herzog BA, Brown JM, et al:Prognostic Value of Cardiovascular Magnetic Resonance and Single-Photon Emission Computed Tomography in Suspected Coronary Heart Disease:Long-Term Follow-up of a Prospective, Diagnostic Accuracy Cohort Study. Ann Intern Med 165:1-9, 2016

25) Meloni A, Al-Saadi N, Torheim G, et al:Myocardial first-pass perfusion:influence of spatial resolution and heart rate on the dark rim artifact. Magn Reson Med 66:1731-1738, 2011