循環器ジャーナル67巻4号

2019年10月発行

特集 冠動脈疾患のリスク管理のフロントライン Ⅰ．冠動脈疾患イベントリスクをどう評価する？

冠動脈イメージング（IVUS・OCT）でどう評価する？

著者： 嶋村邦宏¹ 久保隆史¹

所属機関： ¹和歌山県立医科大学循環器内科

ページ範囲：P.560 - P.565

Point
・OCTは，IVUSと比較して優れた画像分解能を有しており，プラークの形態の詳細な評価が可能で，冠動脈硬化の進展やプラークの不安定化を生体内で観察できる．
・NIRS-IVUSはIVUSによるプラークの形態評価に加えて脂質コアの存在を評価可能であり，脂質性プラークのサイズをlipid-core burden index（LCBI）により半定量的に評価できる．
・OCTにより確認されるTCFAやマクロファージの浸潤，NIRS-IVUSにより確認される高いmaxLCBI値などが冠動脈イベント発症に関連する可能性があり，今後，イメージングモダリティの進歩とさらなる研究が必要である．

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