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雑誌文献

循環器ジャーナル67巻4号

2019年10月発行

文献概要

特集 冠動脈疾患のリスク管理のフロントライン Ⅱ.冠動脈疾患リスクファクターをどう管理する?

中性脂肪はどこまで下げる?

著者: 磯尾直之1 塚本和久1

所属機関: 1帝京大学医学部内科学講座

ページ範囲:P.600 - P.606

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・中性脂肪(TG)につき空腹時150mg/dL,非空腹時175mg/dLをカットオフとして高TG血症のスクリーニングを行い,さらにレムナントやsmall dense LDLの増加の有無を把握する.これらの増加がある場合は空腹時TG<150mg/dLを目標に治療介入する.特に2型糖尿病症例ではより厳格に(例えばTG<115mg/dL)することが望ましい.

参考文献

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10) Chan DC, Watts GF, Barrett PH, et al:Relationships between cholesterol homoeostasis and triacylglycerol-rich lipoprotein remnant metabolism in the metabolic syndrome. Clin Sci(Lond)104:383-388, 2003
11) Katsiki N, Nikolic D, Montalto G, et al:The role of fibrate treatment in dyslipidemia:an overview. Curr Pharm Des 19:3124-3131, 2013
12) Ginsberg HN, Elam MB, Lovato LC, et al:Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med 362:1563-1574, 2010
13) Blazing MA, Giugliano RP, Cannon CP, et al:Evaluating cardiovascular event reduction with ezetimibe as an adjunct to simvastatin in 18, 144 patients after acute coronary syndromes:final baseline characteristics of the IMPROVE-IT study population. Am Heart J 168:205-212, 2014
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掲載誌情報

出版社:株式会社医学書院

電子版ISSN:2432-3292

印刷版ISSN:2432-3284

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