循環器ジャーナル69巻4号

2021年10月発行

特集 プレシジョン・メディシン時代における腫瘍循環器学の重要性 Ⅰ章　腫瘍循環器学とは

疫学研究からみた腫瘍循環器学の必要性

著者： 大倉裕二¹

所属機関： ¹新潟県立がんセンター新潟病院腫瘍循環器科（循環器内科）

ページ範囲：P.522 - P.528

Point
・がんと心臓病は危険因子を共有しているため，がん患者は心臓病を合併しやすい．
・心臓病の危険因子への介入は，がんと心臓病の双方を予防する．
・不全心由来の液性因子ががんの増殖を促進する現象が注目されている．

参考文献

1) Edwards BK, Noone AM, Mariotto AB, et al:Annual Report to the Nation on the status of cancer, 1975-2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer. Cancer 120:1290-1314, 2014

2) Navi BB, Reiner AS, Kamel H, et al:Arterial thromboembolic events preceding the diagnosis of cancer in older persons. Blood 133:781-789, 2019

3) Navi BB, Reiner AS, Kamel H, et al:Risk of arterial thromboembolism in patients with cancer. J Am Coll Cardiol 70:926-938, 2017

4) Strongman H, Gadd S, Matthews A, et al:Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers:a population-based cohort study using multiple linked UK electronic health records databases. Lancet 394:1041-1054, 2019

5) Sturgeon KM, Deng L, Bluethmann SM, et al:A population-based study of cardiovascular disease mortality risk in US cancer patients. Eur Heart J 40:3889-3897, 2019

6) Herrmann J:From trends to transformation:where cardio-oncology is to make a difference. Eur Heart J 40:3898-3900, 2019

7) van Es N, Le Gal G, Otten HM, et al:Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism:A Systematic Review and Meta-analysis of Individual Patient Data. Ann Intern Med 167:410-417, 2017

8) Vinter N, Christesen AMS, Fenger-Grøn M, et al:Atrial Fibrillation and Risk of Cancer:A Danish Population-Based Cohort Study. J Am Heart Assoc 7:e009543, 2018

9) Søgaard KK, Farkas DK, Ehrenstein V, et al:Pericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality. Circulation 136:996-1006, 2017

10) Banke A, Schou M, Videbaek L, et al:Incidence of cancer in patients with chronic heart failure. a long-term follow-up study. Eur J Heart Fail 18:260-266, 2016

11) Tini G, Bertero E, Signori A, et al:Cancer Mortality in Trials of Heart Failure with Reduced Ejection Fraction:A Systematic Review and Meta-Analysis. J Am Heart Assoc 9:e016309, 2020

12) Hasin T, Gerber Y, McNallan SM, et al:Patients with heart failure have an increased risk of incident cancer. J Am Coll Cardiol 62:881-886, 2013

13) Hasin T, Gerber Y, Weston SA, et al:Heart Failure After Myocardial Infarction Is Associated With Increased Risk of Cancer. J Am Coll Cardiol 68:265-271, 2016

14) Selvaraj S, Bhatt DL, Claggett B, et al:Lack of Association Between Heart Failure and Incident Cancer. J Am Coll Cardiol 71:1501-1510, 2018

15) Boffetta P, Malhotra J:Impact of Heart Failure on Cancer Incidence:A Complicated Question. J Am Coll Cardiol 71:1511-1512, 2018

16) de Boer RA, Meijers WC, van der Meer P, et al:Cancer and heart disease:associations and relations. Eur J Heart Fail 21:1515-1525, 2019

17) Lau ES, Paniagua SM, Liu E, et al:Cardiovascular Risk Factors are Associated with Future Cancer. JACC CardioOncol 3:48-58, 2021

18) Meijers WC, Maglione M, Bakker SJL, et al:Heart Failure Stimulates Tumor Growth by Circulating Factors. Circulation 138:678-691, 2018

19) Bhatia S:Genetics of Anthracycline Cardiomyopathy in Cancer Survivors:JACC:CardioOncology State-of-the-Art Review. JACC CardioOncol 2:539-552, 2020

20) Garcia-Pavia P, Kim Y, Restrepo-Cordoba MA, et al:Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy. Circulation 140:31-41, 2019

21) Ⅱ-2　心不全．日本脳卒中学会，日本循環器学会，他：脳卒中と循環器病克服第二次5ヵ年計画．http://www.j-circ.or.jp/five_year/files/JCS_five_year_plan_2nd.pdf

22) Okura Y, Takayama T, Ozaki K, et al:Burden of cardiovascular disease in Japanese cancer patients and survivors:a single cancer-center study in Niigata City. Int J Clin Oncol 24:196-210, 2019

23) Okura Y, Takayama T, Ozaki K, et al:Future projection of cancer patients with cardiovascular disease in Japan by the year 2039:a pilot study. Int J Clin Oncol 24:983-994, 2019