循環器ジャーナル69巻4号

2021年10月発行

特集 プレシジョン・メディシン時代における腫瘍循環器学の重要性 Ⅱ章　がん医療の進歩と腫瘍循環器学

がん放射線療法に関連した心血管合併症（RACD）

著者： 志賀太郎¹

所属機関： ¹がん研有明病院腫瘍循環器・循環器内科

ページ範囲：P.557 - P.565

Point
・強度変調放射線治療（IMRT），定位放射線治療（SRT）のほか，粒子線治療といった高精度放射線療法により，患者個々へのオーダーメイド的治療が可能となり，心臓照射が回避され，RACD発症リスクが劇的に低減している．
・RACDでは晩期障害が主体であり，慢性心膜疾患，冠動脈病変，心筋症，弁膜疾患そして伝導障害の多くが数年から数十年の経過をもって顕在化する．
・RACDは晩期発症が多く，診断を見逃さぬようRACDについての患者教育が肝要である．
・高血圧，喫煙など心血管疾患リスク因子の適正管理は，RACDのリスク低減に極めて重要である．

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