循環器ジャーナル70巻1号

2022年01月発行

特集 心筋症診療のフロントライン—概念から最新の治療まで Ⅲ章　病理

心筋症の病理

著者： 池田善彦¹

所属機関： ¹国立循環器病研究センター病理部病理診断科

ページ範囲：P.23 - P.32

Point
・心筋炎の中では，ステロイドや免疫抑制療法が有効な好酸球性，巨細胞性，肉芽腫性，ループス心筋炎の診断は重要である．心筋炎疑診例での凍結組織を用いた迅速診断は有用である．
・二次性心筋症の診断には，PAS，diastase PAS，oil red O，酸ホスファターゼなどの特殊染色，Gb3，LAMP 2，ATGL，PLIN 2，AL-κ，AL-λ，ATTR，AA，dystrophinⅠ・Ⅱ・Ⅲ，dystrophin A・B，PD-L1，ubiquitinなどの免疫染色，電顕による検索が有用である．

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