循環器ジャーナル71巻3号

2023年07月発行

特集 心臓リハビリテーションのエビデンスを極める Ⅲ.各分野のトピックスを知る

サルコペニアのトピックス

著者： 河野裕治¹² 井澤英夫³ 大高洋平²

所属機関： ¹藤田医科大学病院リハビリテーション部 ²藤田医科大学医学部リハビリテーション医学Ⅰ講座 ³藤田医科大学医学部循環器内科学

ページ範囲：P.411 - P.418

POINT
・サルコペニアとは，加齢に伴う骨格筋量の低下と身体機能の低下を示す．
・心不全患者では，多くの背景因子の影響によりサルコペニアを合併しやすい．
・サルコペニアに対しては包括的心臓リハビリテーションが重要である．

参考文献

1）Okura Y, Ramadan MM, Ohno Y, et al. Impending epidemic : future projection of heart failure in Japan to the year 2055. Circ J 2008 ; 72 : 489-91.

2）日本循環器学会，日本心不全学会．2021年JCS/JHFSガイドライン　フォーカスアップデート版　急性・慢性心不全診療．2021　https://www.j-circ.or.jp/cms/wp-content/uploads/2021/03/JCS2021_Tsutsui.pdf

3）Rosenberg IH. Sarcopenia : origins and clinical relevance. J Nutr 1997 ; 127 : 990S-1S.

4）Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al ; European Working Group on Sarcopenia in Older People. Sarcopenia : European consensus on definition and diagnosis : Report of the European Working Group on Sarcopenia in Older People. Age Ageing 2010 ; 39 : 412-23.

5）Chen LK, Liu LK, Woo J, et al. Sarcopenia in Asia : consensus report of the Asian Working Group for Sarcopenia. J Am Med Dir Assoc 2014 ; 15 : 95-101.

6）Chen LK, Woo J, Assantachai P, et al. Asian Working Group for Sarcopenia : 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc 2020 ; 21 : 300-7.

7）Katano S, Yano T, Ohori K, et al. Novel prediction equation for appendicular skeletal muscle mass estimation in patients with heart failure : Potential application in daily clinical practice. Eur J Prev Cardiol 2021 ; 28 : e18-21.

8）Zhang Y, Zhang J, Ni W, et al. Sarcopenia in heart failure : a systematic review and meta-analysis. ESC Heart Fail 2021 ; 8 : 1007-17.

9）伊藤貴史，河野裕治，青柳陽一郎，他．フレイルを呈する高齢心不全患者のサルコペニア・カヘキシアの実態調査．心臓リハ　2021 ; 27 : 34-9．

10）Hirsch CH, Sommers L, Olsen A, et al. The natural history of functional morbidity in hospitalized older patients. J Am Geriatr Soc 1990 ; 38 : 1296-303.

11）Izawa H, Yoshida T, Ikegame T, et al ; Japanese Association of Cardiac Rehabilitation Standard Cardiac Rehabilitation Program Planning Committee. Standard Cardiac Rehabilitation Program for Heart Failure. Circ J 2019 ; 83 : 2394-8.

12）Kono Y, Izawa H, Aoyagi Y, et al. Predictive impact of early mobilization on rehospitalization for elderly Japanese heart failure patients. Heart Vessels 2020 ; 35 : 531-6.

13）Yin J, Lu X, Qian Z, et al. New insights into the pathogensis and treatment of sarcopenia in chronic heart failure. Theranostics 2019 ; 9 : 4019-29.

14）日本循環器学会，日本心臓リハビリテーション学会．2021年改訂版　心血管疾患におけるリハビリテーションに関するガイドライン．2021　https://www.j-circ.or.jp/cms/wp-content/uploads/2021/03/JCS2021_Makita.pdf

15）Kono Y, Izawa H, Aoyagi Y, et al. The difference in determinant factor of six-minute walking distance between sarcopenic and non-sarcopenic elderly patients with heart failure. J Cardiol 2020 ; 75 : 42-6.

16）Jewiss D, Ostman C, Smart NA. The effect of resistance training on clinical outcomes in heart failure : A systematic review and meta-analysis. Int J Cardiol 2016 ; 221 : 674-81.

17）Vlassara H, Spiegel RJ, Dovalet DS, et al. Reduced plasma lipoprotein lipase activity in patients with malignancy-associated weight loss. Horm Metab Res 1986 ; 18 : 698-703.

18）Pisters PW, Pearlstone DB. Protein and amino acid metabolism in cancer cachexia : investigative techniques and therapeutic interventions. Crit Rev Clin Lab Sci 1993 ; 30 : 223-72.

19）Piepoli MF, Conraads V, Corrà U, et al. Exercise training in heart failure : from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail 2011 ; 13 : 347-57.

20）Dideriksen K, Reitelseder S, Holm L. Influence of amino acids, dietary protein, and physical activity on muscle mass development in humans. Nutrients 2013 ; 5 : 852-76.

21）Mitchell CJ, Churchward-Venne TA, West DWD, et al. Resistance exercise load does not determine training-mediated hypertrophic gains in young men. J Appl Physiol 2012 ; 113 : 71-7.

22）Kikuchi N, Nakazato K. Low-load bench press and push-up induce similar muscle hypertrophy and strength gain. J Exerc Sci Fit 2017 ; 15 : 37-42.

23）Kamiya K, Yamamoto T, Tsuchihashi-Makaya M, et al. Nationwide Survey of Multidisciplinary Care and Cardiac Rehabilitation for Patients With Heart Failure in Japan-An Analysis of the AMED-CHF Study. Circ J 2019 ; 83 : 1546-52.