1)Ghofrani HA, Schermuly RT, Rose F, et al. Sildenafil for long-term treatment of nonoperable chronic thromboembolic pulmonary hypertension. Am J Respir Crit Care Med 2003 ; 167 : 1139-41.
2)Michelakis ED, Tymchak W, Noga M, et al. Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension. Circulation 2003 ; 108 : 2066-9.
3)Galiè N, Ghofrani HA, Torbicki A, et al. Sildenafil Citrate Therapy for Pulmonary Arterial Hypertension. N Engl J Med 2005 ; 353 : 2148-57.
4)Galie N, Brundage BH, Ghofrani HA, et al. Tadalafil therapy for pulmonary arterial hypertension. Circulation 2009 ; 119 : 2894-903.
5)Oudiz RJ, Brundage BH, Galie N, et al. Tadalafil for the treatment of pulmonary arterial hypertension : a double-blind 52-week uncontrolled extension study. J Am Coll Cardiol 2012 ; 60 : 768-74.
6)日本循環器学会,日本肺高血圧・肺循環学会,日本呼吸器学会,他.肺高血圧症治療ガイドライン(2017年改訂版).2018
7)Ogawa A, Satoh T, Tamura Y, et al. Survival of Japanese Patients With Idiopathic/Heritable Pulmonary Arterial Hypertension. Am J Cardiol 2017 ; 119 : 1479-84.
8)Tamura Y, Kumamaru H, Inami T, et al. Changes in the Characteristics and Initial Treatments of Pulmonary Hypertension Between 2008 and 2020 in Japan. JACC Asia 2022 ; 2 : 273-84.
9)Galie N, Barbera JA, Frost AE, et al. Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension. N Engl J Med 2015 ; 373 : 834-44.
10)Humbert M, Kovacs G, Hoeper MM, et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J 2022 ; 43 : 3618-731.
11)Ghofrani HA, Galie N, Grimminger F, et al. Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med 2013 ; 369 : 330-40.
12)Archer SL, Djaballah K, Humbert M, et al. Nitric Oxide Deficiency in Fenfluramine- and Dexfenfluramine-induced Pulmonary Hypertension. Am J Respir Crit Care Med 1998 ; 158 : 1061-7.