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雑誌文献

循環器ジャーナル72巻2号

2024年04月発行

文献概要

特集 心エコー 何をどこまで評価できるか? Ⅲ. 心エコーを活かして構造的心疾患を診断・治療する

心房性機能性MR 心エコー診断と治療方針は?

著者: 阿部幸雄1

所属機関: 1大阪市立総合医療センター循環器内科

ページ範囲:P.290 - P.296

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POINT
・心房拡大とそれに伴う弁輪拡大が主因で,後尖のhamstringing現象や弁尖の代償的リモデリング不足も関与している.
・軽度の左室拡大と左室収縮機能低下を伴っている場合もある.
・薬物治療で改善しない場合は,カテーテル・アブレーション治療や外科手術,カテーテル的僧帽弁手術を考慮する.

参考文献

1)日本循環器学会.2020年改訂版 弁膜症治療のガイドライン.https://www.j-circ.or.jp/cms/wp-content/uploads/2020/04/JCS2020_Izumi_Eishi.pdf(cited 2023 Dec 1)
2)Otsuji Y, Handschumacher MD, Schwammenthal E, et al. Insights from three-dimensional echocardiography into the mechanism of functional mitral regurgitation : direct in vivo demonstration of altered leaflet tethering geometry. Circulation 1997 ; 96 : 1999-2008.
3)Yiu SF, Enriquez-Sarano M, Tribouilloy C, et al. Determinants of the degree of functional mitral regurgitation in patients with systolic left ventricular dysfunction : A quantitative clinical study. Circulation 2000 ; 102 : 1400-06.
4)Otsuji Y, Handschumacher MD, Liel-Cohen N, et al. Mechanism of ischemic mitral regurgitation with segmental left ventricular dysfunction : three-dimensional echocardiographic studies in models of acute and chronic progressive regurgitation. J Am Coll Cardiol 2001 ; 37 : 641-8.
5)Otsuji Y, Kumanohoso T, Yoshifuku S, et al. Isolated annular dilation does not usually cause important functional mitral regurgitation : comparison between patients with lone atrial fibrillation and those with idiopathic or ischemic cardiomyopathy. J Am Coll Cardiol 2002 ; 39 : 1651-6.
6)Kwan J, Shiota T, Agler DA, et al. Geometric differences of the mitral apparatus between ischemic and dilated cardiomyopathy with significant mitral regurgitation : real-time three-dimensional echocardiography study. Circulation 2003 ; 107 : 1135-40.
7)Abe Y, Takahashi Y, Shibata T. Functional mitral regurgitation, updated : ventricular or atrial? J Echocardiogr 2020 ; 18 : 1-8.
8)Takahashi Y, Abe Y, Sasaki Y, et al. Mitral valve repair for atrial functional mitral regurgitation in patients with chronic atrial fibrillation. Interact Cardiovasc Thorac Surg 2015 ; 21 : 163-8.
9)Machino-Ohtsuka T, Seo Y, Ishizu T, et al. Novel mechanistic insights into atrial functional mitral regurgitation-3-dimensional echocardiographic study. Circ J 2016 ; 80 : 2240-8.
10)Ito K, Abe Y, Takahashi Y, et al. Mechanism of atrial functional mitral regurgitation in patients with atrial fibrillation : A study using three-dimensional transesophageal echocardiography. J Cardiol 2017 ; 70 : 584-90.
11)Gertz ZM, Raina A, Saghy L, et al. Evidence of atrial functional mitral regurgitation due to atrial fibrillation : reversal with arrhythmia control. J Am Coll Cardiol 2011 ; 58 : 1474-81.
12)Kagiyama N, Hayashida A, Toki M, et al. Insufficient leaflet remodeling in patients with atrial fibrillation : association with the severity of mitral regurgitation. Circ Cardiovasc Imaging 2017 ; 10 : e005451.
13)Abe Y, Akamatsu K, Ito K, et al. Prevalence and prognostic significance of functional mitral and tricuspid regurgitation despite preserved left ventricular ejection fraction in atrial fibrillation patients. Circ J 2018 ; 82 : 1451-8.
14)Akamatsu K, Abe Y, Matsumura Y, et al. Etiology of Atrial Functional Mitral Regurgitation : Insights from Transthoracic Echocardiography in 159 Consecutive Patients with Atrial Fibrillation and Preserved Left Ventricular Ejection Fraction. Cardiology 2020 ; 145 : 511-21.
15)Xu B, Kawata T, Nakao T, et al. Mitral valvular coaptation-zone area is associated with the severity of atherosclerosis assessed by cardio-ankle vascular index. Int Heart J 2021 ; 62 : 552-8.
16)Takahashi Y, Abe Y, Murakami T, et al. Mid-term results of valve repairs for atrial functional mitral and tricuspid regurgitations. Gen Thorac Cardiovasc Surg 2020 ; 68 : 467-76.
17)Doldi P, Stolz L, Orban M, et al. Transcatheter mitral valve repair in patients with atrial functional mitral regurgitation. JACC Cardiovasc Imaging. 2022 ; 15 : 1843-51.
18)Tanaka T, Sugiura A, Öztürk C, et al. Transcatheter edge-to-edge repair for atrial secondary mitral regurgitation. JACC Cardiovasc Interv 2022 ; 15 : 1731-40.

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:2432-3292

印刷版ISSN:2432-3284

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