臨床検査49巻5号

2005年05月発行

今月の主題 マイクロアレイ技術の進歩 各種アレイによる応用研究

DNAマイクロアレイによる消化器癌のテーラーメイド医療

著者： 嶋田裕¹ 辻本豪三²

所属機関： ¹京都大学医学研究科腫瘍外科 ²京都大学薬学研究科ゲノム創薬科学

ページ範囲：P.522 - P.529

〔SUMMARY〕　消化器癌で考えられるテーラーメイド治療としては①鑑別診断，②予後再発予測，③化学療法または放射線療法感受性予測，④郭清範囲や治療計画の為のリンパ節転移予測が挙げられる．しかしながら，消化器癌ではマイクロアレイに基づくテーラーメイド治療が実践された報告はまだ認められない．今後テーラーメイド医療として成り立つには，マイクロアレイのデータにより患者を振り分けて治療または診断を行う検証が必要である．〔臨床検査　49：522-529，2005〕

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