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臨床検査58巻3号

2014年03月発行

文献概要

今月の特集2 知っておくべき睡眠呼吸障害のあれこれ

睡眠呼吸障害の病態

著者: 葛西隆敏1

所属機関: 1順天堂大学 医学部循環器内科・循環呼吸睡眠医学講座

ページ範囲:P.350 - P.357

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●睡眠呼吸障害(SDB)は閉塞性睡眠時無呼吸(OSA)と中枢性睡眠時無呼吸(CSA)に大別される.

●OSAは上気道の閉塞および狭小化に起因する.

●CSAは呼吸コントロールシステムの不安定さに起因する.

●OSAは心血管疾患の発症および進展,CSAは心血管疾患の進展につながる.

参考文献

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14)Kasai T, Bradley TD:Obstructive sleep apnea and heart failure: pathophysiologic and therapeutic implications. J Am Coll Cardiol 57:119-127,2011
15)Aurora RN, Punjabi NM:Obstructive sleep apnoea and type 2 diabetes mellitus: a bidirectional association. Lancet Respir Med 1:329-338,2013
16)Guilleminault C, Eldridge FL, Simmons FB, et al:Sleep apnea in eight children. Pediatrics 58:23-30,1976
17)Tan HL, Gozal D, Kheirandish-Gozal L:Obstructive sleep apnea in children: a critical update. Nat Sci Sleep 5:109-123,2013
18)Jeans WD, Fernando DC, Maw AR, et al:A longitudinal study of the growth of the nasopharynx and its contents in normal children. Br J Radiol 54:117-121,1981
19)Vlahandonis A, Walter LM, Horne RS:Does treatment of SDB in children improve cardiovascular outcome? Sleep Med Rev 17:75-85,2013

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1367

印刷版ISSN:0485-1420

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