臨床検査59巻8号

2015年08月発行

今月の特集1 臨床検査の視点から科学する老化

副甲状腺機能および代謝性骨疾患と老化

著者： 竹内靖博¹

所属機関： ¹虎の門病院内分泌センター

ページ範囲：P.736 - P.742

Point

●老化によって二次性副甲状腺機能亢進症が生じる．

●二次性副甲状腺機能亢進症は，骨吸収を促進することによって骨粗鬆症をもたらす．

●老化による腎機能低下は，線維芽細胞増殖因子23（FGF23）の分泌亢進を端緒として骨ミネラル代謝の障害をもたらす．

●老化によるさまざまな内分泌障害が骨脆弱性の原因となる．

参考文献

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