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雑誌文献

臨床検査65巻5号

2021年05月発行

文献概要

今月の特集 薬剤耐性(AMR)対策の現状と今後

医療機関における薬剤耐性微生物の感染対策

著者: 坂本史衣1

所属機関: 1聖路加国際病院QIセンター感染管理室

ページ範囲:P.530 - P.535

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●薬剤耐性微生物(MDRO)は,汚染された手指,器具,環境表面との直接および間接接触によって伝播する.

●全ての患者についてMDROの有無を把握することは不可能であるので,手指衛生をはじめとする標準予防策の実施率を日頃から高く維持することがMDROの伝播を防ぐうえで重要である.

●MDROを保菌していることが判明している患者には,標準予防策に加えて接触予防策を追加することが推奨されている.また,感染リスクとなり得る環境への対策も重要である.

●新型コロナウイルス感染症の流行に伴い,MDROの出現や伝播のリスクが高まっているという指摘がある.MDROは,あらゆる医療機関に常に存在するリスクとして対応する必要がある.

参考文献

1)Tischendorf J, de Avila RA, Safdar N:Risk of infection following colonization with carbapenem-resistant Enterobactericeae: A systematic review. Am J Infect Control 44:539-543,2016
2)Zervou FN, Zacharioudakis IM, Ziakas PD, et al:MRSA colonization and risk of infection in the neonatal and pediatric ICU: a meta-analysis. Pediatrics 133:e1015-e1123,2014
3)Centers for Disease Control and Prevention (CDC):Guideline for isolation precautions: preventing transmission of infectious agents in healthcare settings, 2007(https://www.cdc.gov/infectioncontrol/guidelines/isolation/index.html)(最終アクセス:2020年11月9日)
4)World Health Organization (WHO):Guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosa in health care facilities, 2017(https://www.who.int/infection-prevention/publications/guidelines-cre/en/)(最終アクセス:2020年11月9日)
5)World Health Organization (WHO):Guidelines on core components of infection prevention and control programmes at the national and acute health care facility level, 2016(https://www.who.int/infection-prevention/publications/ipc-components-guidelines/en/)(最終アクセス:2020年11月9日)
6)World Health Organization (WHO):Evidence of hand hygiene to reduce transmission and infections by multidrug resistant organisms in health-care settings(https://www.who.int/gpsc/5may/MDRO_literature-review.pdf?ua=1)(最終アクセス:2020年11月9日検索)
7)Banach DB, Bearman G, Barnden M, et al:Duration of Contact Precautions for Acute-Care Settings. Infect Control Hosp Epidemiol 39:127-144,2018
8)Kirkland KB:Taking off the gloves: toward a less dogmatic approach to the use of contact isolation. Clin Infect Dis 48:766-771,2009
9)Mitchell BG, Dancer SJ, Anderson M, et al:Risk of organism acquisition from prior room occupants: a systematic review and meta-analysis. J Hosp Infect 91:211-217,2015
10)Ontario Agency for Health Protection and Promotion (Public Health Ontario), Provincial Infectious Diseases Advisory Committee:Best practices for environmental cleaning for prevention and control of infections in all health care settings, 3rd ed, Queen's Printer for Ontario, Toronto, 2018
11)Marra AR, Schweizer ML, Edmond MB:No-Touch Disinfection Methods to Decrease Multidrug-Resistant Organism Infections: A Systematic Review and Meta-analysis. Infect Control Hosp Epidemiol 39:20-31,2018
12)Anderson DJ, Moehring RW, Weber DJ, et al:Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection). Lancet Infect Dis 18:845-853,2018
13)Parkes LO, Hota SS:Sink-Related Outbreaks and Mitigation Strategies in Healthcare Facilities. Curr Infect Dis Rep 20:42,2018
14)Kanamori H, Weber DJ, Rutala WA:Healthcare Outbreaks Associated With a Water Reservoir and Infection Prevention Strategies. Clin Infect Dis 62:1423-1435,2016
15)Hota S, Hirji Z, Stockton K, et al:Outbreak of multidrug-resistant Pseudomonas aeruginosa colonization and infection secondary to imperfect intensive care unit room design. Infect Control Hosp Epidemiol 30:25-33,2009
16)Kotay S, Chai W, Guilford W, et al:Spread from the Sink to the Patient: In Situ Study Using Green Fluorescent Protein (GFP)-Expressing Escherichia coli To Model Bacterial Dispersion from Hand-Washing Sink-Trap Reservoirs. Appl Environ Microbiol 83:e03327-16,2017
17)Hopman J, Tostmann A, Wertheim H, et al:Reduced rate of intensive care unit acquired gram-negative bacilli after removal of sinks and introduction of ‘water-free’ patient care. Antimicrob Resist Infect Control 6:59,2017
18)Shaw E, Gavald L, Càmara J, et al:Control of endemic multidrug-resistant Gram-negative bacteria after removal of sinks and implementing a new water-safe policy in an intensive care unit. J Hosp Infect 98:275-281,2018
19)Getahun H, Smith I, Trivedi K, et al:Tackling antimicrobial resistance in the COVID-19 pandemic. Bull World Health Organ 98:442-442A,2020
20)Rawson TM, Moore LSP, Zhu N, et al:Bacterial and fungal co-infection in individuals with coronavirus: A rapid review to support COVID-19 antimicrobial prescribing. Clin Infect Dis 2:ciaa530,2020

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1367

印刷版ISSN:0485-1420

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