文献詳細
文献概要
今月の特集 造血器・リンパ系腫瘍のWHO分類 第5版
B細胞優位の腫瘍様病変/Bリンパ芽球性白血病/リンパ腫
著者: 高見昭良1
所属機関: 1愛知医科大学医学部内科学講座血液内科
ページ範囲:P.735 - P.737
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●B細胞優位の腫瘍様病変が新たに加えられた.
●Bリンパ芽球性白血病/リンパ腫(B-ALL)診断の基本は依然形態観察とフローサイトメトリー解析である.
●B-ALL with TCF3::HLF fusion,B-ALL with BCR::ABL1-like features,B-ALL with ETV6::RUNX1-like features,B-ALL with other defined genetic abnormalitiesが追加された.
●現行の保険診療ではB-ALLの細分類は困難である.
●B細胞優位の腫瘍様病変が新たに加えられた.
●Bリンパ芽球性白血病/リンパ腫(B-ALL)診断の基本は依然形態観察とフローサイトメトリー解析である.
●B-ALL with TCF3::HLF fusion,B-ALL with BCR::ABL1-like features,B-ALL with ETV6::RUNX1-like features,B-ALL with other defined genetic abnormalitiesが追加された.
●現行の保険診療ではB-ALLの細分類は困難である.
参考文献
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8)Lilljebjörn H, Henningsson R, Hyrenius-Wittsten A, et al:Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia. Nat Commun 7:11790,2016
9)Nguyen-Khac F, Bidet A, Troadec MB, et al:The 5th edition of the WHO classification of haematolymphoid tumors: comments from the Groupe Francophone de Cytogénétique Hématologique (GFCH). Leukemia 37:946-947,2023
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