臨床検査68巻5号

2024年05月発行

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今月の特集 肥満と健康障害

内臓脂肪型肥満

著者： 武市幸奈¹³ 松田やよい¹ 小川佳宏²³

所属機関： ¹九州大学病院内分泌代謝・糖尿病内科（第三内科） ²九州大学大学院医学研究院病態制御内科学（第三内科） ³九州大学病院栄養管理部

ページ範囲：P.644 - P.651

Point

●肥満は体脂肪分布の違いから，内臓脂肪型肥満と皮下脂肪型肥満に大別される．

●脂肪組織の機能にはエネルギー調節とアディポサイトカインの産生・分泌がある．

●内臓脂肪の過剰な蓄積は，アディポサイトカイン産生異常やインスリン抵抗性を惹起し，糖尿病，脂質異常症や高血圧症ならびに心血管疾患を誘発する．

●日本人は白色人種と比較して，非肥満やごく軽度の肥満であっても内臓脂肪蓄積がみられ，糖尿病などの代謝異常や心血管疾患の合併リスクが高い．

●肥満を体格指数（BMI）のみで評価するのではなく内臓脂肪蓄積の観点から捉えたメタボリックシンドロームの概念は，わが国の肥満診療において大きな意味をもつ．

参考文献

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